Recent advances in molecular biology bring us new predictive tools of multi-gene signature and newly targeted therapy against HER family and cycline-dependent kinase in breast cancer. On the other hand, breast cancer incidence in Japan is increasing in number and the mortality rate remains high. In this session, current strategy for the treatment of breast cancer is reviewed from the results of several trials organized in Japan: a neoadjuvant trial to compare goserelin and anastrozole with goserelin and tamoxifen for premenopausal and hormone-receptor positive breast cancer patients STAGE , efficacy of screening to compare mammography and breast ultrasound with mammography alone for premenopausal women at age J-Stage , utility of TS-1 monotherapy for the first-line chemotherapy of advanced or metastatic breast cancer SELECT BC and clinical benefit of capecitabine against residual disease for breast cancer patients who received primary chemotherapy followed by breast surgery CREATE-X. These trials were carried out from several questionnaires raised by Japanese investigators.
10-year survival rate for cancer climbs to 56.3 percent
Japanese Cancer Organisations - 日本癌组织 | CancerIndex
Cancer as a cause of death has been constantly increasing in Japan, and it became the leading cause of death in Figure 1. Japan had a baby boomer generation, namely those born in — just after World War II, as well as a second generation of baby boomers. The first generation of baby boomers is now in their mids, an age when cancers occur frequently. Accordingly, the number of cancer patients is increasing, and the cancer burden on society is becoming increasingly heavier.
Breast cancer is the most commonly occurring cancer in women and the second most common cancer overall. There were over 2 million new cases in The Continuous Update Project Panel judged that there was strong evidence that consumption of alcoholic drinks, greater birthweight and adult attained height are causes of premenopausal breast cancer. The panel also judged that there is strong evidence that vigorous physical activity and greater body fatness protect against premenopausal breast cancer more information about this unusual finding on greater body fatness can be found in Appendix 2 of Body fatness and weight gain. The Panel judged that there was strong evidence that consumption of alcoholic drinks, greater body fatness throughout adulthood, adult weight gain and adult attained height are causes of postmenopausal breast cancer.
Scientists say they've found a new way to help determine whether specific genetic abnormalities are likely to make people sick, a step toward avoiding a vexing uncertainty that can surround DNA test results. Researchers used genetic engineering to create thousands of tiny variations in a Some 70 percent of women with early-stage breast cancer and an intermediate risk of cancer recurrence can safely skip chemotherapy after their tumors have been removed, U.